Medizinische Genetik Ι Pharmakogenetik

Pharmakogenetik

Cytochrom P450 1A1
(Aryl Kohlenwasserstoff-Hydroxylase, Cyp1A1-Gen, MIM *108330)

Cytochrom P450 1A2
(Aromatic compound inducible, Cyp1A2-Gen, MIM +124060)

Cytochrom P450 1B1
(Microsomal Monooxidase, Cyp1B1-Gen, MIM *601771)

Cytochrom P450 2A6
(Coumarin 7-Hydroxylase, Cyp2A6-Gen, MIM +122720)

Cytochrom P450 2C9
(Warfarin/Tolbutamid-Hydroxylase, Cyp2C9-Gen, MIM *601130)

Cytochrom P450 2C19
(Mephenytoin 4-Hydroxylase, Cyp2C19-Gen, MIM *124020)

Cytochrom P450 2D6
(Debrisoquine 4-Hydroxylase, Cyp2D6-Gen, MIM +124030)

Cytochrom P450 2E1
(Ethanol inducible P450, Cyp2E1-Gen, MIM *124040)

Cytochrom P450 3A4
(Glucocorticoid inducible P450, Nifedipin Hydroxylase, Cyp3A4-Gen, MIM *124010)

Dihydropyrimidin Dehydrogenase
(Fluoruracil-Toxicity, DPYD-Gen, MIM +274270)

Epoxide Hydroxylase
(Microsomal, EPHX1-Gen, MIM 132810)

Glutathion-S-Transferase M1
(Liver- and Fibroblast-specific, GSTM1-Gen, MIM 138350)

Glutathion-S-Transferase M3
(Brain-specific, GSTM3-Gen, MIM 138390)

Glutathion-S-Transferase T1
(Liver- and Erythrocyte-specific, GSTT1-Gen, MIM *600436)

Glutathion-S-Transferase P1
(Fatty acid ethyl ester synthase III, GSTP1-Gen, MIM *134660)

N-Acetyl-Transferase Typ1
(Arylamine N-Acetyl transferase Type1, NAT1-Gen, MIM *108345)

N-Acetyl-Transferase Typ2
(Arylamine N-Acetyl transferase Type2, NAT2-Gen, MIM *612182)

Sulfotransferase 1A1
(Phenol-, SULT1A1Gen, MIM *171150)

Sulfotransferase 1C1
(Hydroxylamin, SULT1C1Gen, MIM *602385)

Superoxid Dismutase Typ 2
(Mn-abhängig, SOD2, MIM *147460)

Superoxid Dismutase Typ 3
(SOD3, MIM *185490)

Thiopurin-S-Methyltransferase
(Mercaptopurin-Toxicity, TPMT, MIM *187680)