DNA methylation analysis
Analysing CpG methylation is a core element of epigenetic research. On the basis of the MassARRAY technology, Bioglobe offers you services in the area of methylation analysis.
Promoter regions of gnes of your choice or any other sequence portions with putative regulatory properties can be ordered for analysis. Assay design and evaluation is software aided and will be adjusted to particular sequence and project requirements by our experts. The system's inherent flexibility guarantees a high level of reliability, sensitivity (down to 5% methylation) and accuracy (5% CV) together with simultaneous analysis of multiples CpG-sites in one reaction. Typically about 90% of CpG-sites will be analyzed simultaneously in amplicons ranging from 350-500 bp. That way Bioglobe offers a fast and efficient methylation screening for mid and high throughput.